Retail_Fashion: 2025 Outlook Quote by Vikram Kankaria, Co-Founder & CEO, Fashor:

"As we step into 2025, India’s fashion industry continues to evolve at an unprecedented pace, driven by a growing appetite for affordable, stylish, and versatile clothing among modern Indian women. With the Indian ethnic wear market projected to reach $19 billion by 2025, the demand for contemporary, size-inclusive, and design-forward options is at an all-time high.

At Fashor, we are committed to redefining affordable fashion with a relentless focus on quality, craftsmanship, and inclusivity. Our vision for 2025 centers on expanding our footprint across India and internationally, with plans to open 100 exclusive brand outlets (EBOs) while continuing to serve millions of women through our thriving online channels.

We see a tremendous opportunity in blending traditional craftsmanship with modern trends, making ethnic and fusion wear more accessible to women of all sizes and backgrounds. Through collaborations, innovative campaigns like ‘Dil Se Indian,’ and an unwavering dedication to customer satisfaction, we aim to empower women to embrace their individuality with confidence and style.

As we embark on this journey, we remain steadfast in our mission to position Fashor as a leading force in the Indian fashion landscape, celebrating the elegance, diversity, and spirit of Indian women.

Zee Telugu to premiere global blockbuster Kalki 2898 AD in Telugu language on 12th January!

Hyderabad, 6^th January 2025: This Sankranti, Zee Telugu is all set to telecast the action blockbuster starring Rebel star Prabhas, Kalki 2898 AD, on 12^th January at 5:30 pm. Directed by Nag Ashwin, this cinematic masterpiece has shattered box office records, earned over ₹1200 crore and made history. With Zee Telugu set to bring this epic to television screens nationwide, millions can soon experience the grandeur of Kalki 2898 AD from the comfort of their homes.

Zee Telugu gives its viewers an engaging and entertaining start to the New Year with the telecast of Kalki 2898 AD. The partnership between Vyjayanthi Movies and Zee highlights their shared commitment to delivering exceptional entertainment. While the movie premieres on 12^th January, the film adds to Zee’s impressive lineup of blockbuster movies, solidifying its status as a leader in entertainment.

Set in a world on the brink of apocalypse, the movie blends mythology, science fiction, and stunning visuals. Featuring stars like Amitabh Bachchan, Kamal Haasan, Prabhas, and Deepika Padukone, the film showcases an epic battle of cosmic proportions, remarkable performances, and breathtaking VFX. From its record-breaking debut to global acclaim, Kalki 2898 AD has captivated audiences and redefined cinematic storytelling.

Swapna Dutt, Producer at Vyjayanthi Movies, says, "Bringing Kalki 2898AD to Zee is an honour that feels like destiny unfolding. Zee has been the heartbeat of Indian entertainment, delivering stories that resonate with every corner of this nation. This film has carved a special place in the hearts of our audiences, and we’re ecstatic that viewers across the country will get to experience its magic together. Blending action, drama, mythology, and fantasy, the Nag Ashwin directorial is the ultimate family watch—a kaleidoscope of genres wrapped in one breathtaking experience. We couldn’t have asked for a better partner than Zee to project this saga onto the widest canvas possible. What’s even more exciting is that the PAN India movie, Kalki 2898 AD, will have its first-ever World Television Premiere in Telugu, on Zee Telugu. This is a cinematic masterpiece for the ages, and Zee Telugu’s audience is the perfect crowd to experience it.”

Bharat Ranga, Managing Director Rancorp Media Private Limited, elucidates “We are so proud to distribute Kalki a milestone in Indian Cinema to India’s pioneering TV platform Zee. The premiere of this PAN-India blockbuster will take place first on Zee Telugu, bringing it to viewers in its original Telugu language. This is a delightful marriage between global impact Cinema and World’s largest Indian platform that we so heartily executed.”

Talking about the premiere, the Chief Content Officer of Zee Telugu - Anuradha Gudur, said “Kalki 2898 AD is a fusion of Indian mythology with modern narrative. It bridges the gap between our past and our future in a modern setting. The film focuses on Lord Vishnu's 10th avatar, and reimagines mythology through a futuristic lens, making it relatable to young audiences. Zee Telugu's World Television Premiere of this cinematic masterpiece in Telugu language, reflects its commitment to delivering world-class entertainment that celebrates Indian roots while embracing modern thinking. We are excited for the premiere of this blockbuster movie first on Zee Telugu and offer our viewers a Sankranti delight.”

Get ready for a Sankranti celebration like never before as Zee Telugu brings you an unmissable edge-of-the-seat entertainer with Kalki 2898 AD! This cinematic masterpiece is set to redefine your festive vibes.

So, don’t miss the roller coaster ride of emotions and action as Kalki 2898 AD premieres this Sunday at 5:30 pm, only on Zee Telugu!

Essen Speciality Films Limited Sets New Standard by Incorporating More Than 50% Post-Consumer Recycled Material in Artificial Plants and Flowers

Rajkot, 06 January, 2025  – Essen Speciality Films Limited (ESFL) has once again reaffirmed its commitment to sustainability by incorporating more than 50% post-consumer recycled materials into its artificial plants and flowers. This groundbreaking initiative underscores the company’s dedication to reducing environmental impact while promoting responsible manufacturing practices.

Driving a Greener Future, One Product at a Time

Essen Speciality Films Limited is dedicated to designing products that beautify homes while preserving the environment. By incorporating sustainable materials and processes, Essen continues to make a positive impact. Many of ESFL’s products, including artificial plants, yoga mats and table covers, are manufactured from post-consumer recycled materials, reducing plastic waste and minimizing reliance on virgin materials. ESFL sources its recycled inputs from Global Recycled Standard (GRS) certified suppliers, ensuring ethical and environmentally responsible practices. Additionally, Essen’s products are made from BPA-free materials, further support sustainable and healthy lifestyles.

A Testament to Excellence: Finalist at PRS Awards 2024

Essen Speciality Films Limited’s innovative approach has earned industry recognition, as the company was a proud finalist in the Recycled Plastic Product category at the Plastic Recycle India Awards (PRS Awards) 2024. This honor highlights ESFL’s unwavering commitment to leveraging recycled materials and creating eco-friendly products, setting a benchmark in the industry.

Commenting on this milestone, Mr. Pallav Doshi, Whole-Time Managing Director of Essen Speciality Films Limited, stated, “At Essen, our commitment towards sustainability remains strong in all product offerings. We understand the importance of reducing our carbon footprint and have introduced several initiatives to cut waste, save resources, and encourage responsible manufacturing. By integrating environmental care into our business strategies, we are proud to support a more sustainable future for our planet.”

This recognition highlight ESFL's dedication to innovation and sustainability. Essen continues to inspire industries to adopt greener practices and remains steadfast in its mission to create products that harmonize with nature.

About Essen Speciality Films Limited:

Essen Speciality Films Limited is a leading global manufacturer of sustainable plastic products, offering a diverse range including Bath Area and Accessories, Artificial Plants & Flowers, Kitchen & Dining, Storage & Organization, Fitness & Lifestyle, and Outdoor & Utility Products. Established in 2002 as a small family business, Essen has since grown into a powerhouse supplying top-quality products to Fortune 500 Retailers and OEMs across 47+ countries. Backed by over 37 years of machine manufacturing expertise from Rajoo Engineers Ltd., Essen prides itself on its commitment to sustainability, exclusively utilizing renewable and recycled polymers in its manufacturing processes.

For more information, visit https://www.essenspeciality.com

Industrial & warehousing dominate with USD 2.5 Billion in realty investments for 2024

·       Institutional inflows in Indian realty highest in past 5 years at USD 6.5 Bn, up 22% YoY

·       Office segment witnessed USD 2.3 Bn inflows, primarily driven by foreign investors

·       Investments in residential segment rose by 46% YoY, at USD 1.1 Bn

·       Domestic investments drove 1/3rd of the inflows, surging by 27%YoY in 2024

·       Mumbai attracted majority of the inflows with 24% share in 2024

Gurgaon, 06 January 2025: Institutional investments in Indian real estate touched a remarkable USD 6.5 billion inflows in 2024, marking a substantial 22% increase from the previous year's USD 5.4 billion. This surge reflects strong investor appetite for Indian real estate and marks an annual high for both domestic and foreign investments since 2020.

The fourth quarter of 2024 was particularly robust, with investments totaling USD 1.9 billion—2.3X times compared to the same period in 2023. This end-year momentum contributed significantly to higher investment volumes for 2024. Interestingly, domestic investments were significant in Q4 2024 and accounted for 43% of the inflows during the final quarter. This underscores the growing confidence of India-based institutional investors alongside sustained interest from international counterparts.

In 2024, the Industrial & warehousing segment accounted for the highest share in overall real estate investment volumes at 39%, surpassing the office segment. Manufacturing and industrial growth in the country was robust throughout 2024 and was reflected in the performance of macro-economic indicators such as Manufacturing Purchasing Manager’s Index (PMI) and Index of Industrial Production (IIP). At USD 1.1 billion, residential segment too witnessed substantial growth, rising 46% compared to 2023 levels. Overall, at USD 4.3 billion, foreign inflows continued to drive annual real estate investments at 66% share, while domestic investments too witnessed a steady rise, surging 27% YoY during the year.

“Private equity investments in Indian real estate have witnessed strong momentum in 2024 buoyed by robust domestic growth and sustained investor confidence. With a record USD 6.5 billion inflows in 2024, Indian realty investments have been the highest since 2020. Interestingly, APAC investors drove almost one-third of the foreign inflows in the country’s real estate during the year. Looking ahead, Tier-I cities will continue to attract majority of the capital, amidst government impetus on infrastructure development and ‘Make in India’ initiative. While global investors’ confidence is likely to remain upbeat, 2025 is likely to see increased capital deployment from domestic players across office, residential and industrial assets,” said Badal Yagnik, Chief Executive Officer, Colliers India.

Investment inflows (USD million) trend–

Asset Class	2023	2024	2024 vs 2023 (% YoY Change)	Q4 2023	Q3 2024	Q4 2024	Q4 2024 vs Q4 2023 (% YoY Change)	Q4 2024 vs Q3 2024 (% QoQ change)
Office	3,022.5	2,338.9	-23%	135.5	616.3	825.3	509%	34%
Residential	788.9	1,149.1	46%	81.0	384.8	118.2	46%	-69%
Alternate assets*	649.1	39.5	-94%	418.7	-	18.5	-96%	-
Industrial & Warehousing	877.6	2,541.6	190%	187.1	95.2	735.7	293%	673%
Mixed use	42.3	390.0	822%	-	52.4	84.4	-	61%
Retail	-	104.4	-	-	-	104.4	-	-
Total	5,380.4	6,563.5	22%	822.3	1,148.7	1886.5	129%	64%

*Note: Alternate assets include data centers, life sciences, senior housing, holiday homes, student housing, schools etc.

Investment inflows were limited for alternate assets in Q3 2024, mixed use assets in Q4 2023 and retail in 2023 and Q3 2024

The institutional flow of funds includes investments by family offices, foreign corporate groups, foreign banks, proprietary books, pension funds, private equity, real estate fund-cum-developers, foreign-funded NBFCs, listed REITs and sovereign wealth funds. The data has been compiled as per available information in the public domain

Source: Colliers

Industrial & warehousing investments in 2024 surge, 2.9X times compared to 2023

During 2024, institutional investments in Industrial & warehousing segment rose and were almost thrice the inflows in 2023. The segment attracted USD 2.5 billion investments, accounting for 39% of the total inflows, closely followed by the office segment at 36% share. Rising investments in the Industrial & warehousing segment is a testament to healthy domestic activity, enhancements in logistics efficiency, and India's improving capabilities as a global manufacturing hub. Foreign investments drove over 80% of the total inflows in the segment during the year.

"The year 2024, was a watershed year for real estate investments in India, wherein industrial & warehousing asset inflows surpassed annual investments in the office segment. With USD 2.5 billion inflows, large-sized deals drove industrial & warehousing investments in 2024. Rising demand for superior quality Grade A developments and evolving supply-chain models will continue to incentivise investors in consolidating industrial & warehousing assets in the country. Furthermore, manufacturing scale-up and healthy consumption levels are likely to attract domestic and global investments in both ready-to-use as well as developmental industrial assets, going ahead," said Vimal Nadar, Senior Director & Head of Research, Colliers India.

Despite subdued activity in the first few quarters of 2024, investments in the office segment picked up pace in the second half of the year. With USD 2.3 billion inflows, the segment accounted for a 36% share during 2024, and closely followed industrial & warehousing segment. Foreign investments accounted for about 77% of the inflows in office segment during the year. Additionally, residential assets too witnessed a notable growth during the year at USD 1.1 billion, witnessing a substantial 46% surge on an annual basis driven by sustained interest from domestic players.

Mumbai drove majority of the annual inflows, with 58% share in office assets

While multi-city deals corresponded to an overall 39% share, Mumbai, with about USD 1.6 billion inflows accounted for 24% of the real estate investments in the country during 2024. At 58%, office segment attracted majority of the annual inflows in the city on account of investment in select developmental assets. This was followed by industrial & warehousing assets which accounted for 20% of the real estate investments in Mumbai during 2024. Investment inflows in Bengaluru, Chennai and Delhi NCR also remained steady and accounted for 8-9% share each during the year.

 

City-wise investment inflows

City	Q4 2023	Q4 2024	Investment share in Q3 2024 (%)	Q4 2024 vs Q4 2023 (%)	2023	2024	Investment share 2024 (%)	2024 vs 2023 (%)
Bengaluru	21.2	104.4	6%	392%	263.0	590.4	9%	124%
Chennai	60.7	13.3	1%	-78%	193.1	547.5	8%	184%
Delhi NCR	135.6	103.3	5%	-24%	627.5	520.8	8%	-17%
Hyderabad	-	-	-	-	127.3	300.9	5%	136%
Kolkata	-	75.3	4%	-	-	75.3	1%	-
Mumbai	146.1	1,174.7	62%	704%	731.9	1,581.4	24%	116%
Pune	-	100.0	5%	-	-	369.0	6%	-
Others/ Multi-City	458.7	315.5	17%	-31%	3,437.6	2,578.2	39%	-25%
Total	822.3	1,886.5	100%	129%	5,380.4	6,563.5	100%	22%

Source: Colliers

Note: Investment inflows in Hyderabad were limited in both Q4 2023 & Q4 2024; Investment inflows in Kolkata & Pune were limited in 2023

NONSTOP RETAIL OPENS ITS DOORS IN SOUTH MUMBAI TO OFFER INTERNATIONAL QUALITY PERSONAL MOBILITY AND REHAB PRODUCTS

o   India’s first multi-brand personal mobility store chain for products like electric wheelchairs, incontinence, bathroom safety aids etc inaugurated by Sangeeta Bijlani

o   1st NONSTOP flagship store in Mumbai with plans to set up 100+ by the end of 2027

Revolutionizing standards in healthcare with respect to personal mobility and rehab products for combating ageing, injuries and disability, GREENPIONEER MOBILITY PRIVATE LIMITED has launched its first flagship store called ‘NONSTOP’ at Prabhadevi in Mumbai. In addition to bringing cutting edge products from global leaders like WHILL from Japan, Vermeiren & Wheeleo from Belgium; My Cocoon, Michael Graves Design, iWalkFree, GoChirp - from USA, MEXPLE and AiroMEDIC are private label Brand designed in the USA and many more in the pipeline, NONSTOP offers expert consultations, personalized product recommendations, hands-on trials and excellent after-sales support marking its dedication to enhancing lives through innovative, high-quality and accessible solutions. The Mumbai outlet is India's First Multi-brand Mobility Store offering an entire range of products that provide comfort, support and freedom to individuals with personal mobility and rehabilitation needs.

Famous actress Sangeeta Bijlani, who inaugurated this world class multi-brand retail showroom remarked, “I could notice technologically advanced wheelchairs, walkers, bathroom safety aids, orthopaedic cushions and wellness essentials that will be a boon for our seniors or those with temporary or permanent disability. Some of the equipment was very user friendly and could be operated with the touch of a button.”

Mobility aids help to improve the functional capacity of people affected by disability, injury, chronic conditions or age or while recovering from surgery. Mobility devices like walkers, wheelchairs, or similar power-driven devices take some of the weight through arms and distribute it over a wider surface area thereby reducing the stress placed on hips and knees. Better weight distribution not only makes walking more comfortable, but also offers joint protection. These mobility aids help individuals navigate their environments more easily, reduce pain, increase confidence, and overall increase their independence.

Mobility aids can provide significant benefits to individuals affected by a range of medical conditions, including arthritis, cerebral palsy, developmental disabilities, diabetic ulcers and wounds, fractures or broken bones, injuries, and walking impairments resulting from brain injury or stroke. Access to such hi-tech, smooth functioning devices also increases the employability of these individuals.

Says Iftekhar Ahmed, CEO & Founder of NONSTOP Retail, “The new store aligns with NONSTOP’s vision of empowering individuals with greater independence, dignity, and quality of life. One can shop here for Mobility Aids, Monitoring Devices, Walkers, Electric & Manual Wheelchairs & Medical Products which are contemporary technology. This store represents a strategic step in NONSTOP’s growth journey, strengthening its presence in key markets and solidifying its reputation as a go-to destination for personal mobility and wellness solutions. Considering the top most hospitals around and product value, this location makes all the sense to take the premium positioning for the brand.”

With rise in India's elderly population, chronic illnesses become more frequent, and as awareness about disabilities grows, increased demand for rehab and mobility products that are of high-quality has spread throughout the country. Key factors fueling the growth in demand for mobility aids are higher geriatric population due to improved health facilities leading to an extended human lifespan, reduction in customs duty recently for select Assistive technology products to 5% making them more affordable, launch of 17 schemes by Government of India for Divyang etc. Buoyed by the tremendous response to its earlier ventures, the company has drawn up ambitious plans to launch 100+ stores across India over the next 3-4 years.

The Mumbai NONSTOP store launch includes exciting offers, exclusive discounts, and complimentary consultations for early visitors. Special events like live product demos, expert talks, and interactive workshops highlight innovative mobility solutions. For further details log onto https://gononstop.in

Uorfi Javued Pays Visit To Cancer Patients Aid Association, Urges Netizens To Donate

*Uorfi Javed Highlights the Need To Donate To Cancer Patients, Visits  Cancer Patients Aid Association*

In a heartfelt initiative, Uorfi Javed visited a Cancer Patients Aid Association and gauged attention to the growing need for donations to support individuals battling cancer. Known for her vibrant personality, bold fashion choices, and much more, Uorfi Javed took quality time out of her busy schedule and met the youth at the association, offering hope and encouragement to the young faces. 

Uorfi took to her social media handle to share glimpses of her warm visit. The series of pictures showcases her meeting and sharing smiles with the kids, clicking pictures with them and their loved ones. Along with the pictures, she also penned a note, urging netizens to donate to cancer patients, stressing that even the smallest donations can play a vital part in the cause. Her caption read, "Thank you @cpaaindia for all that you do for these kids! Kudos to children’s parents, the strength and efforts it takes to care for a cancer patient 🌹 Requesting people to please donate to @cpaaindia . If you’re seeing this post. No amount is big or small. Kindness goes a long way ! 🍀"

https://www.instagram.com/p/DEbzf8VyPzb/?igsh=YWtjbHBjZnBlOXR2&img_index=1

By leveraging her platform, Uorfi Javed's kind gesture aims to inspire the effort to battle cancer, highlighting that her visit to the association is a catalyst for change. With this, Uorfi Javed has ignited a spark of hope and has urged the netizens to unite in the fight to combat cancer.

Sooraj Pancholi all set to essay Veer Hamirji Gohil in his first biopic! A heroic war based Film to revolve around the Somnath Temple

BUZZ: Sooraj Pancholi To Play An Unsung Warrior In His Maiden Biopic! Story to Revolve Around a War Surrounding Somnath Temple

*BUZZ: Sooraj Pancholi Gears Up for His First Biopic! Actor To Essay Veer Hamirji Gohil in a Story About the Somnath Temple War!

Sooraj Pancholi, known for his fierce screen presence and ability to resonate with the masses, is set to sway the masses by headlining his maiden biopic. The 'Hero' star will be seen essaying the role of an unsung warrior Veer Hamirji Gohil in a film that revolves around the war that took place at the famous Somnath temple in Gujarat. Adding anticipation to the drama, the film will delve into the inspiring tale of unsung warriors who fought and sacrificed their lives to save the temple from intruders during the 14th century AD. Helmed by director Prince Dhiman, the biopic has been shot on a grand scale with opulent sets and recreated palaces.

Beyond this, the actor will be seen sharing the screen space for the first time with the iconic actor Suniel Shetty, Vivek Oberoi, and Akanksha Sharma. To add authenticity, the actors will essay never-seen-before avatars, bringing to the forefront an impactful film that not only promises to keep the masses entertained but also tells a story inspired by real-life incidents. The one-of-a-kind project also boasts authentic action sequences, that promise to elevate the feel and effect of the film's theme. 

By essaying the role of an unsung warrior, Sooraj Pancholi is set to highlight his acting chops as well as his range as a power-packed performer. With a storyline that is expected to deeply connect with the audiences, Suniel Shetty's rich experience in intriguing roles, and Vivek Oberoi's knack for bringing complex characters to life, this mighty collaboration is one that the fans have been eagerly waiting for. As the excitement around the film is palpable, buzz is rife that the makers are set to drop the first glimpse of the project anytime soon.

Apoorva Arora’s Short Film Lipstick Wins Best Short Film Award at Jalgaon Film Festival

Apoorva Arora’s much-anticipated short film Lipstick has achieved a remarkable feat by winning the Best Short Film award at the Jalgaon Film Festival. Directed by a promising filmmaker, the film has been lauded for its poignant narrative that sheds light on the importance of mental health and overcoming unresolved trauma.

Apoorva portrays Diksha, a character who navigates the complexities of life while addressing the impact of past challenges on her present. The audience and critics alike have praised her nuanced performance, which is both heartfelt and inspiring.

Speaking about the achievement, Apoorva shared her excitement:

"This award is a testament to the power of storytelling and the importance of addressing issues like mental health. Diksha’s journey is one that resonated deeply with me, and I’m humbled by the love and recognition the film has received. It’s a reminder that meaningful cinema has the ability to spark conversations and touch hearts."

The win at Jalgaon Film Festival not only highlights Apoorva’s talent but also reinforces her commitment to taking on roles that challenge societal norms and bring vital issues to the forefront.

Ishq Jabariya Actress Siddhi Sharma Finds Peace and Flavor in Rajasthan : . It’s something I really miss here in Mumbai because

Travel has a magical way of refreshing our minds and hearts, and for actress Siddhi Sharma, her recent visit to Rajasthan was nothing short of a soulful retreat. Known for her energetic portrayal of Gulki in Sun Neo's popular show Ishq Jabariya, Siddhi took some time off her hectic shooting schedule to reconnect with her roots and soak in the beauty of her homeland.

Reflecting on her recent getaway, Siddhi shared her heartfelt experience, “Recently, I visited Rajasthan, and what I loved the most about the trip was the beautiful environment at our farm house in Jaipur. The surroundings were full of greenery, mountains, farming areas, and an overall peaceful vibe. If you stand on the terrace, all you can see is greenery, mountains, clouds, birds, and animals. It’s something I really miss here in Mumbai because we don’t usually get to experience this kind of natural beauty in our daily lives.” 

But it wasn’t just the peaceful surroundings that made this trip special. The traditional Rajasthani food added to the charm to which Siddhi said, “The food was unique and special. Since I am originally from Rajasthan, I enjoyed traditional dishes like bajre ki roti served with chutney and jaggery, sathe ki roti, gatte ki sabzi, mangodi ki kadhi, and of course, dal baati churma. These warm, flavorful dishes taste even better in Rajasthan’s environment.  “

The Ishq Jabariya actress further added, “This was my most recent family trip, and I am looking forward to the next one. However, my schedule has been so hectic as I am busy in shoot for my ongoing Sun Neo’s show Ishq Jabariya that I haven’t had the chance to plan anything yet.”

Ishq Jabariya, airing on Sun Neo at 7:30 PM, is an engaging love story centred around Gulki, a determined young woman with big aspirations. The show boasts a stellar cast, including Kamya Panjabi, Siddhi Sharma, and Lakshay Khurana in key roles, bringing depth and emotion to this captivating narrative.

Tune into Sun Neo to watch Ishq Jabariya, every Monday to Saturday at 7:30 PM.

कोकिलाबेन धीरूभाई अंबानी हॉस्पिटलमध्ये अत्याधुनिक CAR-T थेरपीने रुग्णाला आक्रमक रिलॅप्स्ड लिम्फोमातून पूर्णपणे बरे केले

3९ वर्षाचे रिजेश यांच्यासाठी अत्याधुनिक CAR-T उपचारांमुळे २०२४ हे वर्ष नवीन आशेने समाप्त झाले आणि कॅन्सर मुक्त होऊन त्यांनी २०२५ चे स्वागत केले

 

नवी मुंबई, 03 जानेवारी, 2025: युनायटेड स्टेट्स ऑफ अमेरिकेमध्ये आपल्या करियरच्या शिखरावर असलेले कॉर्पोरेट प्रोफेशनल, ३९ वर्षांचे रिजेश आणि त्यांच्या कुटुंबियांना आक्रमक लिम्फोमाच्या रिलॅप्सने खूप मोठा धक्का दिला. हा लिम्फोमा पारंपरिक उपचारांना प्रतिरोधक असल्याने हे सगळेच अतिशय निराश झाले होते. पण कोकिलाबेन धीरूभाई अंबानी हॉस्पिटल, नवी मुंबईमध्ये अभिनव CAR-T थेरपीने रिजेशना कॅन्सरपासून पूर्णपणे मुक्ती मिळवून दिली आणि त्यांचा जीव वाचवला.

ऑक्टोबर २०२३ मध्ये समजले की रिजेशना डिफ्युज लार्ज बी-सेल लिम्फोमा (डीएलबीसीएल) झाला होता, हा नॉन-हॉजकिन लिम्फोमा (एनएचएल) च्या सर्वात सामान्य प्रकारांपैकी एक आहे. त्यांच्यावर स्टॅन्डर्ड फर्स्ट-लाईन उपचार केले गेले, यामध्ये आर-सीएचओपी (R-CHOP) केमोथेरपीचा देखील समावेश होता, यामध्ये सीएनएसमध्ये कॅन्सर पेशींना टार्गेट करण्यासाठी मेथोट्रेक्सेट थेट मणक्याच्या हाडाच्या फ्लुइडमध्ये दिले गेले. या उपचाराने सुरुवातीला काही आशाजनक परिणाम दाखवले पण दुर्दैवाने जून २०२४ मध्ये कॅन्सरने पुन्हा फणा वर काढला.

यावेळी या आजाराने अजून जास्त दुर्मिळ आणि आक्रमक स्वरूप धारण केले होते - हाय-ग्रेड डबल-हिट लिम्फोमा. यामधल्या आनुवंशिक असामान्यता असल्यामुळे हे स्टॅन्डर्ड उपचारांना प्रतिरोधक बनते. आजार जेव्हा दुसऱ्यांदा वर आला तेव्हा त्यामध्ये अजूनच गुंतागुंत निर्माण झालेली होती कारण लिम्फोमा मेंदू आणि मणक्याच्या हाडांपर्यंत पोहोचलेला होता. आता हा आजार उपचारांसाठी एक सर्वात कठीण कॅन्सर बनलेला होता. तेव्हा रिजेश कोकिलाबेन धीरूभाई अंबानी हॉस्पिटल, नवी मुंबईमध्ये हेमेटॉलॉजिस्ट आणि हेमेटो-ऑन्कोलॉजिस्ट, कन्सल्टन्ट बीएमटी आणि सेल्युलर थेरपी (सीएआर-टी) डॉ कुणाल गोयल यांच्याकडे उपचारांसाठी आले.

रिजेश यांच्यावर अतिशय काटेकोरपणे बहु-आयामी उपचार सुरु करण्यात आले. यामध्ये हाय-डोस मेथोट्रेक्सेटवर आधारित केमोथेरपी (MTR), CNS बूस्टसोबत संपूर्ण ब्रेनची रेडिओथेरपी (WBRT) आणि एक टार्गेटेड थेरपी एकलाब्रुटिनिब यांचा समावेश होता. MTR ला ब्लड ब्रेन बॅरियर भेदण्यासाठी आणि सेंट्रल नर्व्हस सिस्टिममध्ये लिम्फोमा पेशींना टार्गेट करण्यासाठी डिझाईन करण्यात आले होते. WBRT चा उपयोग संपूर्ण मेंदूमध्ये रेडिएशन पोहोचवण्यासाठी करण्यात आला होता, तर "बूस्ट" ने अशा विशिष्ट भागांवर अतिरिक्त रेडिएशन केंद्रित केले जिथे कॅन्सर होता. इतके सगळे प्रयत्न करून देखील लिम्फोमा तसाच राहिला आणि मग टीमने एक दुसरा दृष्टिकोन अवलंबिण्याचा निर्णय घेतला, या निर्णयाने आधुनिक वैद्यकशास्त्राच्या सीमा रुंदावल्या.

डॉ कुणाल गोयल यांनी (कैमेरिक अँटीजेन रिसेप्टर टी-सेल थेरपी) Chimeric Antigen Receptor T-cell किंवा CAR-T थेरपीचा उपयोग करण्याचा निर्णय घेतला. CAR-T एक प्रगत इम्युनोथेरपी आहे, यामध्ये कॅन्सर पेशी ओळखून नष्ट करण्यासाठी रुग्णाच्या रोगप्रतिकार पेशींमध्ये बदल केले जातात. डॉ कुणाल गोयल यांनी आपल्या निर्णयाविषयी सांगितले, "CAR-T थेरपी कॅन्सरच्या उपचारांमध्ये एक नवी क्रांती घेऊन आली आहे. ज्यांच्यासाठी उपचारांचे इतर पर्याय समाप्त झाले आहेत अशा आक्रमक आणि रिलॅप्स्ड लिम्फोमाच्या रुग्णांसाठी हे खूपच उपयुक्त आहे. CAR-T मध्ये रुग्णांच्या रोगप्रतिकार शक्तीचा उपयोग केला जातो. या प्रक्रियेमध्ये रुग्णाच्या टी-पेशींना सहभागी केले जाते, या सफेद रक्तपेशी असतात, ज्या शरीराला संसर्ग आणि आजारांविरोधात लढण्यासाठी मदत करतात, प्रयोगशाळेमध्ये या पेशींना कॅन्सर पेशींना टार्गेट करण्यासाठी तयार केले जाते आणि पुन्हा रुग्णाच्या रक्तप्रवाहामध्ये पुन्हा सोडले जाते."

रिजेशच्या टी-पेशी काढून एका विशेष प्रयोगशाळेत पाठवण्यात आल्या, याठिकाणी त्यांच्या पृष्ठभागावर कैमेरिक अँटीजेन रिसेप्टर (CAR) हा एक सिंथेटिक रिसेप्टर एक्स्प्रेस करण्यासाठी अनुवांशिक पद्धतीने इंजिनीयर करण्यात आले. या CAR ला लिम्फोमा पेशींच्या पृष्ठभागावर आढळणारे प्रोटीन ओळखण्यासाठी आणि त्याच्याशी जोडले जाण्यासाठी डिझाईन करण्यात आले होते. T-पेशींना CAR सोबत बदलले गेल्यानंतर त्यांना प्रयोगशाळेमध्ये मल्टिप्लाय केले गेले आणि पुन्हा त्यांच्या शरीरातील रक्तप्रवाहामध्ये सोडले गेले. या "री-इंजिनीयर्ड" CAR-T पेशी आता लिम्फोमा पेशींना अचूकपणे टार्गेट करून नष्ट करू शकत होत्या.

१९ नोव्हेंबर २०२४ रोजी रिजेशवर कोकिलाबेन धीरूभाई अंबानी हॉस्पिटल, नवी मुंबईमध्ये CAR-T थेरपी केली गेली आणि बदलण्यात आलेल्या CAR-T पेशींना त्यांच्या शरीरातील रक्तप्रवाहामध्ये सोडण्यात आले. रिजेशसाठी ही जीव वाचवण्याची शेवटची आणि कदाचित सर्वात चांगली संधी होती. CAR-T थेरपीमुळे घडून आलेला परिणाम हा निव्वळ एक चमत्कार होता. एका महिन्यानंतर पीईटी सीटी स्कॅनमध्ये (PET CT scan) समजले की कॅन्सर पूर्णपणे बरा झाला होता आणि रिजेशच्या शरीरामध्ये लिम्फोमा आढळून आला नाही!

कोकिलाबेन धीरूभाई अंबानी हॉस्पिटल, नवी मुंबईचे चीफ ऑपरेटिंग ऑफिसर डॉ शशिकांत पवार यांनी सांगितले, "कॅन्सर पूर्णपणे बरा होणे ही बाब वैद्यकीय तंत्रज्ञानातील प्रगतीबरोबरीनेच आधुनिक उपचारांची शक्ती देखील दर्शवते. कॅन्सरवरील उपचारांमध्ये CAR-T थेरपी सर्वात आघाडीवर आहे आणि आम्ही प्रयत्न करत आहोत की रिजेशसारख्या रुग्णांना आधुनिक वैद्यकीय प्रगतीचे सर्वात चांगले लाभ मिळावेत, जेणेकरून ते सर्वात गंभीर आणि गुंतागुंतीच्या आजारातून बाहेर यावेत. या केसने रुग्ण आणि कोकिलाबेन धीरूभाई अंबानी हॉस्पिटल नवी मुंबईची टीम या दोघांनाही वर्ष २०२४ ला अतिशय आनंदाने निरोप देण्याची संधी दिली. ही केस आठवण करून देते की, वैद्यकीय क्षेत्राचे भवितव्य हेच असणार आहे आणि ते उज्वल आहे."

Deltin’s ‘MegaPlay’ Event Redefined Year-End Festivities with Six Days of Spectacular Performance

India, 02 January 2025: As 2024 drew to a close, Deltin Royale and Deltin Jaqk set a new benchmark for New Year celebrations with their iconic and eagerly anticipated ‘MegaPlay’ event. Spanning six extraordinary days from December 27, 2024, to January 1, 2025, this meticulously curated extravaganza captivated audiences with a seamless blend of world-class music, spellbinding dance acts, and breathtaking curated performances, establishing itself as a definitive highlight of the year-end festivities.

On New Year’s Eve, Deltin Royale saw a star-studded performance by Rahul Vaidya, the acclaimed singer known for his iconic journey on Indian Idol 1 and Bigg Boss 14. Simultaneously, Deltin Jaqk came alive with Shanmukha Priya, the celebrated Indian Idol 12 finalist, whose powerful voice and captivating stage presence thrilled the audience. The celebrations were further elevated by dynamic performances from the renowned dance duo Tarun & Shivani at Deltin Royale and the Reality TV sensation pair Shivam & Sonali Kar at Deltin Jaqk.

Throughout the event, guests were treated to a diverse array of performances, including mesmerizing Vegas and Bollywood dance medleys, spellbinding illusions, high-energy acrobats, led acts soul-stirring live music and daily lucky draws with exciting prizes to be won. The fusion of these world-class acts and offerings ensured that the event was a multi-sensory experience, offering something for everyone.

Commenting on the success of the event, Mr. Manoj Jain, COO of Delta Corp Ltd, stated, “At Deltin, we’re always committed to pushing the boundaries of what’s possible, and we’re proud to have set a new standard for New Year celebrations in Goa. ‘MegaPlay’ was our tribute to our guests who made 2024 exceptional. The success of this event has laid a strong foundation for us to elevate the Deltin experience even further in 2025 and beyond, as we remain dedicated to innovation and exceeding expectations."

About Deltin:

‘Deltin’, India’s leading brand in luxury gaming and hospitality, is owned by Delta Corp Ltd. (DCL), a publicly listed company which owns and operates casinos and hotels in Goa (India), Sikkim (India), Daman (India)  For more information, please visit www.deltin.com 

Official First Look Poster of "Mukhoshe Manushe Khela - Dark Mind Games": A Corporate Thriller**Kolkata, India - January 3,

 2025 – As the new year sets in, Sabitri Productions, in collaboration with acclaimed director Orpheus Mukhoty, unveiled the first-look poster for their much-anticipated Bengali feature film *Mukhoshe Manushe Khela - Dark Mind Games.* The gripping murder mystery promises to enthrall audiences with its unique take on corporate intrigue.

Starring *Joydip Chakraborty, Priyanka Sarkar, and Subrata Dutta* in pivotal roles, Mukhoshe Manusher Khela revolves around the life of businessman Joy Sanyal (portrayed by Joydip Chakraborty), who becomes entangled in a web of murder conspiracies spun by his rivals. As mysterious deaths occur, Joy is forced to confront the dark secrets of his seemingly perfect world. Priyanka Sarkar plays Nandini, a mysterious corporate associate, while Subrata Dutta essays the role of investigator Manik Sen. Real-life cop *ACP Aloke Sanyal* will also appear in the film as himself.

Actor and writer of Mukhoshe Manushe Khela, Joydip Chakraborty, who hails from Abu Dhabi and boasts extensive experience in theater and short films, expressed his excitement about his feature film debut. "Bringing Mukhoshe Manushe Khela to life has been an exhilarating journey. We can't wait to share this unique corporate thriller with audiences worldwide," he shared.

Director Orpheus Mukhoty (known for Ei Shohore, Boli, Akashee Pullover, and Adhara) remarked, "This film marks a groundbreaking venture into the corporate thriller genre, offering suspense and intrigue from start to finish."

Produced by Sabitri Productions from the UAE, *Mukhoshe Manusher Khela - Dark Mind Games* recently completed filming in Kolkata. The film’s cinematography is by Sourav Dey, with music composed by Kaushik Ghosh. *Abhijit Barman,* *aka ‘Pota’(of Cactus fame)*, has lent his voice to the title track of the film.

*The film is set for a theatrical release in February 2025 in Kolkata and the UAE*

In addition, Sabitri Productions has also ventured into English cinema with their upcoming film *The Phoenix*, which is slated for release in January 2025 and is currently doing the rounds of Film Festivals globally. *Mukhose Manusher Khela* is the first of many of their many Bengali features.

Imperfecto Mehfil by Bel Cibo Debuts in Delhi’s Iconic Omaxe Chowk, Chandni Chowk

Imperfecto

Spanning over 6,000 sq. ft., the restaurant sets a new standard for Mughal-inspired dining

In the heart of Delhi’s historic Chandni Chowk, Omaxe Chowk is redefining the culinary landscape with the opening of Imperfecto Mehfil, the latest venture by Bel Cibo. This restaurant spanning over 6000 sq.ft. combines the grandeur of Mughal-inspired interiors with the flavors of authentic Mughlai cuisine, offering guests a royal dining experience steeped in heritage.

Imperfecto Mehfil immerses diners to a regal era with its baithak-style seating, vintage chandeliers, and intricately designed décor. The menu showcases culinary artistry with signature dishes like Tandoori Raan, Nargisi Kofta, and Akbari Dal, complemented by refreshing beverages such as Mohabbat ka Sharbat. Blending India’s rich heritage with contemporary dining, the restaurant reimagines the culinary experience to deliver a bold fusion of tradition and innovation.

Jatin Goel, Executive Director of Omaxe Group, said: "Our vision for Omaxe Chowk is to establish it as a premier culinary destination, offering a diverse range of dining experiences that celebrate both local and global flavors. Dawatpur, India’s largest food court, is a key part of this vision, featuring an exceptional mix of traditional street food and international cuisine, while also expanding our portfolio with more premium dine-in options. With the addition of Imperfecto Mehfil, we are further enhancing this vision, introducing a refined dining experience that blends regal Mughal aesthetics with exceptional culinary craftsmanship. Omaxe Chowk is quickly becoming the go-to destination for food lovers, making it a true cultural and culinary landmark."

Omaxe Chowk, located in the heart of Chandni Chowk, Delhi, is a premier retail and dining destination that seamlessly blends heritage with modernity. It attracts visitors from all over, offering a diverse shopping experience with a wide range of fashion, accessories, home décor, and electronics, catering to every shopper's needs. Beyond shopping, Omaxe Chowk is a food lover's paradise, featuring a variety of culinary delights from local street food to international flavors. With entertainment options for family outings, social gatherings, or a relaxing day with friends, Omaxe Chowk’s prime location, world-class amenities, and diverse offerings make it the ultimate destination to shop, dine, and unwind—all under one roof.