Swap Kidney Transplant saves lives of two at Apollo Hospitals, Navi Mumbai

In a first for Navi Mumbai, members of two families donate kidneys to each other

Navi Mumbai, 13 September 2022: Apollo Hospitals, Navi Mumbai, a leading tertiary care hospital, successfully performed the first Kidney Swap Transplant surgery in Navi Mumbai. The swap involved two families, the Sithas from Uran and the Sainis from Sion. The families found hope in each other as due to medical concerns, it became impossible for family members to give kidney to their own kin. In a turn of events, Sunanda Sitha, mother of Rahul Sitha, donated kidney to Parvinder Saini, wife of Gurudev Singh and Gurudev Singh donated kidney to Rahul Sitha.

For those suffering with end stage kidney diseases, a kidney transplant is the only treatment and those that do not have find a donor, remain on dialysis. A swap transplant attempts to minimize the shortfall of donors. It is an exchange of organs between two families, who cannot donate the organ to their own family member due to incompatibility concerns such as blood group mismatch or HLA mismatch. A swap transplant addresses the acute shortage of organ donation by enlarging the pool of donors who wish to donate to their family members but cannot due to incompatibility issues.

Sunandha Sitha (49 years) wished to donate a kidney to her son, Rahul Sitha (28 years) and Gurudev Saini (64 years) wished to donate a kidney to his wife, Parvinder Saini (61 years) but neither Sunandha nor Gurudev were compatible matches with their respective family members.

Dr Amolkumar Patil, Consultant, Robotic Urology and Renal Transplant Surgeon said, “Gurudev Saini was A+ and his wife was AB+. She had a high titer of donor specific antibodies (DSA) against her husband and a high risk of rejection (30 - 40 %). She didn’t find any compatible donor in city of Mumbai for the past 18 months. Similarly, Rahul Sitha (O+ve) had high titre blood group antibodies against his mother Sunandha (B+ve). This meant higher cost and higher/ stronger immunosuppression for transplant with increased risk of rejection. With swap transplant, both recipients showed a low titer of DSA and had a high success rate, required less strong drugs and had low chances of infection.”

Dr Amit Langote, Consultant, Nephrology and Transplant Physician, said, “Swap transplant is a potential solution for patients with kidney failure who have a family donor but cannot donate due to compatibility issue. In this case, by swapping, both patients got better kidneys with significant low risk of rejection and resulted in a successful procedure to both families.”

Mr. Santosh Marathe, Regional CEO said, “The patients had been looking for a suitable donor for more than a year. A swap transplant helped them find compatible donors. Due to patients and their families’ cooperation and the trust they put in the doctors, we were successful in performing the first swap transplant in Navi Mumbai, giving a second chance at life to two people. Such procedures give a ray of hope for patients with end-stage renal diseases. Apollo Hospitals Navi Mumbai has been the preferred regional kidney transplant centre attracting patients from distant parts of Maharashtra. Apart from the multi-disciplinary of senior transplant surgeons & senior Nephrologists, we have a high end post-operative care provided in ICU, experienced & qualified nursing staff & medical counsellors to support the program.”